Ivermectin (Stromectol)

Ivermectin tablets comprise an anthelmintic sourced from avermectins, which are extracted from the fermentation of Streptomyces avermitilis. These tablets are utilized for treating various parasitic diseases. Their mechanism involves a targeted interaction with the nervous system of parasites without impacting mammals.

Specifically, Ivermectin exhibits a strong binding affinity to gamma-aminobutyric acid (GABA) and glutamate (GluCl)--regulated chloride channels found in invertebrate nerve and muscle cells.

This interaction leads to paralysis and the eventual demise of the parasite. Ivermectin tablets effectively disrupt the infection cycle, aiding in the prevention of infection spread.

What diseases does it treat?

The drug Ivermectin has successfully passed clinical trials, like many similar drugs aimed at combating parasites. Ivermectin has been successfully tested and used in human treatment for the following diseases:

• onchocerciasis;
• strongyloidiasis of the gastrointestinal tract;
• wuchereriosis;
• ascariasis;
• trichocephalosis;
• filariasis;
• enterobiasis;
• skin syndrome Larva migrans;
• human mite scabies;
• demodicosis;
• rosacea;
• brugioz, etc.

In addition, the medicine copes very well with head lice. Without a doubt, it can also be used for children, who are more susceptible to infection than adults.

Dosage of the drug and release form

In order to cure demodicosis, Ivermectin is prescribed in a dose of 12 mg - this is exactly one tablet of the drug. The highest concentration of anthelmintic medication reaches a person's blood in about three to four hours. The medication penetrates the body tissues quite evenly and smoothly.

Ivermectin in tablet form is rapidly absorbed into the human intestinal mucosa when taken orally. But before using the tablets, it is important to take into account one point - the drug is classified as the first class of danger! Therefore, it is imperative to follow the rules and dosage as recommended in the instructions for use!

Note: Ivermectin is eliminated no longer than after 28 hours. It leaves the body only with feces.

Oral tablets are used to treat people. Creams, gels, lotions, emulsions, and ointments based on the active ingredient Ivermectin for external use have recently undergone clinical trials.

Ivermectin: instructions for use

Before taking Ivermectin tablets, you need to talk with your doctor; just following the instructions in this case may not be enough. It is important to discuss each dosage recommendation with a specialist so that he can prescribe an individual dose for you based on the characteristics of your body.

The instructions recommend calculating dosages in accordance with a person’s body weight. One single dose is equal to 200 mcg per 1 kg of human weight. It turns out that if the patient weighs 70 kg, then his single dose of the drug will be equal to 12 mg. This is just one tablet of Ivermectin.

Taking the drug depends on the degree of infection of the body, as well as on the type of worms. Taking these factors into account, Ivermectin can be taken by an adult up to two doses per day. But it is important to take the next dose only after a few weeks.

As for children, if the child weighs over 15 kg, the dose is 150 mcg per kilogram of the small patient’s body weight. That's what the instructions say. But before you start treating your child on your own, you need to consult a doctor who can prescribe more precise treatment and the right dose of the drug.

What are the side effects of Ivermectin?

• If you use the drug Ivermectin strictly in the doses indicated in the instructions or prescribed by a doctor, then there should be no side effects on the body. If the permissible dose is exceeded, some side effects are possible:
• dizziness and headache;
• loss of strength and weakness;
• itching, rash, and swelling;
• pain in joints and muscles;
• cardiopalmus.

When should Ivermectin not be administered?

Ivermectin tablets should be avoided if you:

• Are allergic to ivermectin or any of its components
• Are pregnant or breastfeeding
• Seek to prevent threadworm infections, as Ivermectin is not used for prevention purposes
• Are afflicted with another infection caused by microfilarial worms such as loa loa, as this heightens the risk of experiencing side effects
• Have asthma
• Are currently taking medications that interact with Stromectol, including diethylcarbamazine citrate, a fast-acting drug used to treat microfilarial infections, as well as warfarin

Overdose

If the recommended dosage is exceeded, the following symptoms may appear: skin rashes, hives, headache, general malaise, lack of coordination, tingling in the hands and feet, abdominal pain, nausea with vomiting, diarrhea, dizziness, difficulty breathing; swelling of the arms, legs, face, ankles. There are no specific detoxification agents. In case of overdose, the victim must rinse the stomach and select symptomatic treatment.